Breast cancer with brain metastasis
Conditions
Interventions
Breast cancer with brain metastasis:none
Sponsors
The Fifth Affiliated Hospital Sun Yat sen University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Patients treated at The Fifth Affiliated Hospital of Sun Yat-sen University from July 1, 2020 to June 30, 2025. 2.Aged = 18 years and < 75 years. 3.No gender restriction. 4.Pathologically confirmed breast cancer. 5.Radiologically confirmed brain metastasis. 6.Received at least one cycle of liposomal doxorubicin-containing therapy during the period of brain metastasis.
Exclusion criteria
Exclusion criteria: 1.No radiological assessment performed after treatment with liposomal doxorubicin-containing regimens; 2.Incomplete medical records or unavailable survival status information; 3.Experienced disease progression following anthracycline use in the advanced stage; 4.Discontinued liposomal doxorubicin treatment due to allergic reactions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Central Nervous System Clinical Benefit Rate (CNS-CBR); | — |
Secondary
| Measure | Time frame |
|---|---|
| Disease Control Rate (DCR);Objective Response Rate (ORR);Central Nervous System Disease Control Rate (CNS-DCR);Safety;Central Nervous System Objective Response Rate (CNS ORR);Clinical Benefit Rate (CBR); | — |
Countries
China
Contacts
Public ContactPeijian Peng
The Fifth Affiliated Hospital Sun Yat sen University
Outcome results
None listed