sarcopenia
Conditions
Interventions
older adults with sarcopenia:none
Sponsors
Zhongda Hospital, Southeast University
Eligibility
Sex/Gender
All
Age
50 Years to 85 Years
Inclusion criteria
Inclusion criteria: Sarcopenia: 1. Age 50-85 years; 2. meet the AWGS 2025 diagnostic criteria for sarcopenia; 3. Able to walk without assistive devices; 4. Able to understand and cooperate with the trial and voluntarily sign the informed consent form. Inclusion criteria for healthy controls: 1. age 50-85 years; 2. Able to walk without assistive devices; 3. Able to understand and cooperate with the trial and voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with hypertension whose blood pressure cannot be controlled (systolic blood pressure >160mmHg or diastolic blood pressure >100mmHg after taking medication); Diabetic patients with poor glycemic control (glycated hemoglobin >11%); 2. Severe cardiac or psychiatric disease (e.g., schizophrenia), severe liver and kidney function disease (e.g., liver cirrhosis, history of kidney stones, renal failure or dialysis), severe organ failure, neuromuscular or skeletal system disease (e.g., osteoporosis, severe osteoarthritis); 3. Presence of severe vestibular dysfunction or foot deformity; 4. Severe speech, audio-visual impairment that prevents normal communication with the researcher, or dementia or obvious depression, unable to understand the content of the questionnaire or scale; 5. Contraindications to MRI, such as ferromagnetic implants such as pacemakers, claustrophobia, etc.; 6. Patients with acute infection or antibiotics within one month prior to screening; 7. Other clinical subjects who are participating in the evaluation that affects the results of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| COP sway area; | — |
Secondary
| Measure | Time frame |
|---|---|
| Berg;Plantar pressure;sEMG;fNIRS;fMRI;Functional Reach Test, FRT; | — |
Countries
China
Contacts
Public ContactWan Ruihan
Zhongda Hospital, Southeast University, Nanjing, Jiangsu
Outcome results
None listed