Abnormalities in the morphology, function or position of teeth, jawbones and facial structures during development, manifested as misaligned teeth, disordered occlusal relationships and asymmetrical facial appearance, etc.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Voluntarily cooperate with this research and sign the informed consent form for the research (for minor subjects, it must be signed by their legal guardians); 2.The diagnosis is clear. Comprehensive fixed orthodontic treatment is required, and the treatment plan involves extracting two first premolars from both the upper and lower jaws. 3.Gender is not limited. Age range: 12 to 35 years old. 4.The molar relationship is Angle Class I or Angle Class II;
Exclusion criteria
Exclusion criteria: 1.Cases where grinding teeth is required for distal movement to create a gap; 2.There is a history of tooth extraction in the molar area (excluding the third molar). 3.There is a molar "scissors bite" relationship; 4.Has received orthodontic treatment or orthognathic surgery treatment; 5.There are missing or impacted teeth (except for the third molars). 6.Suffering from systemic severe diseases (requiring long-term medication), severe periodontitis, congenital cranio-maxillofacial deformities or syndromes; 7.Long-term history of smoking or heavy drinking; 8.Pregnancy or lactation; 9.Receive other clinical trial intervention measures or other trial drugs during orthodontic treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mesial displacement of maxillary first molar (mm); | — |
Secondary
| Measure | Time frame |
|---|---|
| The variation in the near-distal axial inclination of the maxillary canines and the first molars (°);The improvement effect of occlusion;The vertical variation (mm) of the maxillary central incisors and the maxillary first molars;Retraction of the maxillary central incisors (mm);The variation in the width between the bilateral maxillary canines and the width between the first molars (mm);Torque variation (°) of the maxillary central incisors, canines and first molars; | — |
Countries
China
Contacts
Stomatological Hospital of Southern Medical University