Deep Vein Thrombosis
Conditions
Interventions
Gold Standard:In this study, bedside color Doppler ultrasound combined with comprehensive clinical assessment (including underlying diseases, DVT risk factors, clinical signs and symptoms, dynamic lab
Index test:bedside ultrasound machine (Mindray M9, color Doppler mode) and plasma D-dimer analyzer (Mindray automated coagulation analyzer CX-9000)
Sponsors
Meishan City Peoples Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. ICU length of stay = 48 hours (to ensure exposure to ICU-related DVT risk factors); 2. Presence of at least one high-risk factor for DVT (including advanced age =65 years, history of surgery within the past 3 months, mechanical ventilation duration =24 hours, central venous catheterization, malignancy, obesity, etc. [1]); 3. Completion of plasma D-dimer testing and bedside lower extremity venous ultrasound examination within 48 hours of admission; 4. Complete clinical data (including underlying diseases, diagnostic and therapeutic procedures, test results, and follow-up outcomes).
Exclusion criteria
Exclusion criteria: 1. History of lower extremity DVT or pulmonary embolism (which may affect the interpretation of test results); 2. Received anticoagulant therapy (e.g., low molecular weight heparin, warfarin) before ICU admission; 3. Concomitant severe liver or kidney failure (Child-Pugh Class C liver function or serum creatinine >442 µmol/L, which may interfere with D-dimer metabolism); 4. Incomplete ultrasound examination with assessment of only proximal or distal sites; 5. Missing clinical follow-up data, precluding comprehensive evaluation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sensitivity;specificity;positive predictive value;Negative Predictive Value; | — |
Countries
China
Contacts
Public ContactZhang Sha
Meishan City Peoples Hospital
Outcome results
None listed