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Establishment of a machine learning prediction model for early recurrence after hepatic cell carcinoma resection

Establishment of a machine learning prediction model for early recurrence after hepatic cell carcinoma resection

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600123711
Enrollment
Unknown
Registered
2026-04-29
Start date
2026-05-01
Completion date
Unknown
Last updated
2026-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular Carcinoma (HCC)

Interventions

Training Set:Postoperative observation
Validation Set:Postoperative observation

Sponsors

The First Affiliated Hospital of Xi'an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Patients who only accept radical liver resection as the sole treatment method; 2. Have not received transcatheter arterial chemoembolization (TACE), targeted therapy, or immunotherapy before the surgery; 3. Have been diagnosed as hepatocellular carcinoma through preoperative imaging examinations (enhanced CT/magnetic resonance imaging) or postoperative pathology, strictly in accordance with the "Standard for diagnosis and treatment of primary liver cancer (2024 edition)" ; 4. No evidence of extrahepatic metastasis was found in the preoperative imaging examinations; 5. Have no autoimmune diseases. 6. The patient is aged between 18 and 85 years old.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating women; 2. Individuals with autoimmune diseases; 3. Patients with other malignant tumors; 4. Those who have previously received systemic treatment for liver cancer: traditional Chinese medicine, targeted therapy, immunotherapy, etc.; 5. Patients who have previously undergone surgical treatment: liver resection, ablation, TACE, etc.; 6. Patients who have experienced severe allergic reactions to chemotherapy drugs; 7. Unpredictable physical damage.

Design outcomes

Primary

MeasureTime frame
Recurrence-free survival;Brier Score;AUC;C-index;Sensitivity;Specificity;

Secondary

MeasureTime frame
Alkaline Phosphatase, ALP;Albumin, ALB;Hepatitis;Platelet Count, PLT;Aspartate Aminotransferase, AST;Capsule invasion;Microvascular invasion;Fibrinogen, FIB;Alpha-fetoprotein, AFP;Blood loss;Prothrombin Time, PT;Hemoglobin (Hb);Tumor Diameter;Activated Partial Thromboplastin Time, APTT;Cirrhosis;Red Blood Cell Count, RBC;International Normalized Ratio, INR;White Blood Cell Count, WBC;Total Bilirubin, TBIL;Gamma-Glutamyl Transferase (GGT);Direct Bilirubin, DBIL;Total Protein (TP);

Countries

China

Contacts

Public ContactZheng Xin

The First Affiliated Hospital of Xi'an Jiaotong University

zhengxin@xjtufh.edu.cn+86 29 85323215

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 7, 2026