Postoperative pain
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age: 18 - 75 years old; 2. ASA classification: I - III grade; 3. Surgical type: Patients undergoing elective laparoscopic thoracic surgery; 4. Preoperative health condition: No use of opioid drugs or with a history of discontinuation for more than one month.
Exclusion criteria
Exclusion criteria: 1. Allergic to opioids or with a history of severe adverse reactions; 2. Having moderate to severe liver or kidney dysfunction (ALT, AST, creatinine more than twice the normal value); 3. Mental or psychological disorders: including severe anxiety disorder or depression; 4. Having a history of opioid dependence or abuse in the past; 5. Pregnant or lactating women; 6. Patients participating in other interventional trials simultaneously; 7. Patients who were converted to open chest surgery due to surgical needs during the operation; 8. Patients with low oxygen saturation and asthma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence rate of chronic pain within 6 months; | — |
Secondary
| Measure | Time frame |
|---|---|
| Perioperative complications: incidence of itching, nausea, vomiting, and hypoxemia (SpO2<90%) during the intravenous analgesia pump period (48 hours)?Adverse reactions: 1. Dizziness 2. Nightmares or h;The frequency of use of remedial analgesics, the number of effective presses of the analgesic pump, and the time of the first press.; | — |
Countries
China
Contacts
chongqing university cancer hospital