Arrested hydrocephalus
Conditions
Interventions
Gold Standard:According to the latest international guidelines for the diagnosis of hydrocephalus, an Evans’ index >=0.33 is used as a diagnostic criterion.
Index test:Multimodal magnetic resonance imaging, including structural MRI, diffusion tensor imaging, and dynamic diffusion-weighted imaging .
Sponsors
Wuxi Children's Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 3 Years
Inclusion criteria
Inclusion criteria: Case group inclusion criteria: (1) According to the latest international hydrocephalus guideline diagnostic criteria, Evan's>=0.33; (2) Age: 0 to 3 years old; (3) No gender limit. Inclusion criteria for control group: (1) Gender was matched to the case group participating in the brain imaging study, and age was matched to the patient, with an age difference of <=1 year. (2) No mental illness or any serious physical disease. (3) Routine MRI examination was normal.
Exclusion criteria
Exclusion criteria: 1. Suffering from other mental disorders (such as schizophrenia, etc.); 2. Have inherited metabolic diseases; 3. Have a history of severe neurological diseases such as epilepsy and major physical diseases such as craniocerebral injury. 4. Abnormal results of routine MRI examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ependymal surface irregularity index;Sensitivity;Filamentation index;Ependymal surface area;Full width at half maximum, and apparent diffusion coefficient;Specificity;Accuracy;Receiver operating characteristic curve; | — |
Countries
China
Contacts
Public ContactHaoxiang Jiang; Lu Qiu
Wuxi Children's Hospital
Outcome results
None listed