Cancer pain
Conditions
Interventions
Group B: Oxycodone Sustained-release Tablets Group:None
Group A: Oxycodone Hydrochloride Tablets Group:None
Sponsors
Beijing Luhe Hospital, Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Over 18 years old; 2.Pathology or cytology confirmed malignant tumor, accompanied by moderate cancer pain (NRS: 4-6 points); 3.Initial use of oxycodone may require adjustment of opioid dosage; 4.Expected survival time of more than 3 months; 5.Able to cooperate to complete pain assessment; 6.The patient or family voluntarily signs the informed consent;
Exclusion criteria
Exclusion criteria: 1.History of opioid abuse or allergy; 2.Pregnant women and women in the gestational period; 3.Combined use with other potent opioids (such as fentanyl patches); 4.Cognitive impairment or inability to independently report pain scores; 5.Patient cannot take orally; 6.Other researchers believe situations unsuitable for participation;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average NRS pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Average daily breakthrough pain episodes during treatmen;Time to first cancer pain escalation treatment;Adverse Reaction Incidence Rate;EORTC QLQ-C30 Quality of Life Total Score;Medication Adherence (missed medication rate assessed by pill counting and electronic administration records); | — |
Countries
China
Contacts
Public ContactDong Yan
Beijing Luhe Hospital, Affiliated to Capital Medical University
Outcome results
None listed