Post-thoracoscopic pain
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who consent to participate in this trial protocol; 2. Patients undergoing elective thoracoscopic surgery; 3. Male or female, aged 18 to 65 years; 4. Body mass index (BMI) ranging from 18 to 28 kg/m²; 5. American Society of Anesthesiologists (ASA) physical status classification Grade ? to ?.
Exclusion criteria
Exclusion criteria: 1. Patients with cognitive or mental disorders who are unable to cooperate; 2. Patients with coagulation dysfunction; 3. Patients with infection or tumor at the puncture site; 4. Patients with severe hepatic and renal insufficiency (Child-Pugh Class C or eGFR < 30 mL/min/1.73m²); 5. Patients with a previous history of chronic neuropathic pain; 6. Patients with a history of illicit drug use; 7. Patients with a history of allergy to study-related drugs such as ropivacaine; 8. Patients refusing postoperative analgesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score;postoperative nausea and vomiting; | — |
Secondary
| Measure | Time frame |
|---|---|
| nerve block puncture time;nerve block puncture depth;intraoperative remifentanil consumption;intraoperative propofol consumption;time of first pressing of patient-controlled intravenous analgesia pump;number of effective PCIA boluses within 48 h postoperatively;number of rescue analgesic administrations;serum interleukin-6 (IL-6);serum tumor necrosis factor-a (TNF-a);incidence of nerve block-related complications;respiratory depression; | — |
Countries
China
Contacts
The First People's Hospital of Fuzhou City