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The Role of Obesity-Aging Interaction Pathway in the Occurrence of Metabolic Syndrome: A Cohort Study Based on the Population in Western Guangdong

The Role of Obesity-Aging Interaction Pathway in the Occurrence of Metabolic Syndrome: A Cohort Study Based on the Population in Western Guangdong

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600123683
Enrollment
Unknown
Registered
2026-04-28
Start date
2026-05-01
Completion date
Unknown
Last updated
2026-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity, Metabolic Syndrome

Interventions

Sponsors

Affiliated Hospital of Guangdong Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: 1. Age 18-75 years, residents of western Guangdong or have lived there for >=5 years; 2. Informed consent obtained and written agreement signed; 3. Able to cooperate with completing questionnaires and physical examinations.

Exclusion criteria

Exclusion criteria: Exclusion Criteria: 1. Diagnosed with MetS (CDS criteria); 2. Presence of severe illnesses (cancer, end-stage renal disease, heart failure NYHA class III-IV), with expected life expectancy <5 years (e.g., advanced diseases); 3. Long-term use of glucocorticoids/immunosuppressants; 4. History of major surgery, trauma, or acute infectious disease in the past 6 months; 5. Pregnant or breastfeeding women; 6. Known endocrine diseases causing secondary obesity (e.g., Cushing's syndrome, uncontrolled hypothyroidism); 7. Inability to complete follow-up or having communication barriers; 8. Plans to move out of the western Guangdong region within 3 years.

Design outcomes

Primary

MeasureTime frame
Metabolic symptom;

Secondary

MeasureTime frame
TyG- Aging Index;

Countries

China

Contacts

Public ContactJiayuan Wu

Affiliated Hospital of Guangdong Medical University

87537665@qq.com+86 759 2387156

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 7, 2026