viral hepatitis B induced liver fibrosis
Conditions
Interventions
patients with chronic hepatitis B:None
healthy control group:None
Sponsors
Third Xiangya Hospital, Central South University
Eligibility
Sex/Gender
All
Age
21 Years to 64 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria of patients of viral hepatitis B : 1. The patient has been HBsAg positive for at least 6 months; 2. Agree to liver biopsy histological examination; 3. Individuals without severe claustrophobia and able to cooperate with MRI scanning for breathing and breath holding requirements. Inclusion criteria of healthy volunteers: no severe claustrophobia, no history of hepatitis and other chronic liver diseases, and no obvious abnormality in two and a half pairs of hepatitis B B and liver function tests after inclusion.
Exclusion criteria
Exclusion criteria: 1. Patients with co-infection of other hepatitis viruses, alcoholic and non-alcoholic liver diseases, and other liver diseases; 2. Patients who have not obtained biopsy specimens and thus cannot undergo histopathological examination; 3. Patients whose images contain a large amount of respiratory artifacts and cannot be post-processed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| true diffusion coefficient;pseudo diffusion coefficient;perfusion fraction;area under the curve; | — |
Countries
China
Contacts
Public ContactRong Pengfei
Third Xiangya Hospital , Central South University
Outcome results
None listed