Pediatric sepsis
Conditions
Interventions
Viral sepsis group:None
Bacterial sepsis group:None
Sponsors
Kunming Children’s Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.The subjects are mainly recruited from the PICU of Kunming Children's Hospital and collaborating multi-center hospitals; 2. Participants must fulfill the pediatric sepsis criteria published by the Society of Critical Care Medicine (infection + PSS >= 2); 3. Positive viral PCR or targeted NGS in the viral group,and documented bacterial infection in the bacterial group; 4. Post-natal age > 28 days and <= 18 years; 5. Volunteers who agreed to participate and provided written informed consent; 6. Complete medical records available.
Exclusion criteria
Exclusion criteria: 1. Neonates or infants born at <37 weeks’ gestation; 2. Previous malignancy or hematologic disorders; 3. Primary immunodeficiency; 4. Children whose legal guardians decline participation; 5. Incomplete medical records.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Inflammatory markers;Cardiac biomarkers;Liver function;Kidney function;Coagulation picture;Blood gas analysis;Pathogen type; | — |
Secondary
| Measure | Time frame |
|---|---|
| Imaging study;Mechanical ventilation parameters; | — |
Countries
China
Contacts
Public ContactFu Hongmin
Kunming Children’s Hospital
Outcome results
None listed