Postpartum Depression
Conditions
Interventions
Normal Saline Group 2(C2):An equal volume of normal saline was sprayed into each bilateral nostril 15 minutes prior to puncture.
Normal Saline Group 1(C1):An equal volume of normal saline was sprayed into the unilateral nostril 15 minutes prior to puncture.
Experimental Group 2(S2):A dose of 25 µg dexmedetomidine was administered to each of the bilateral nostrils 15 minutes prior to puncture.
Experimental Group 1(S1):A dose of 25 µg dexmedetomidine was administered via nasal spray into the unilateral nostril 15 minutes prior to the performance of puncture.
Sponsors
Hefei First People's Hospital
Eligibility
Sex/Gender
Female
Age
21 Years to 39 Years
Inclusion criteria
Inclusion criteria: 1. Both primiparas and multiparas are eligible. 2. Age 21–39 years, 26 <= BMI <= 33 kg/m^2. 3. ASA I or Level I, full-term, cephalic presentation, single fetus. 4. Complete relevant prenatal examinations before labor analgesia; cervical dilation 2–3 cm, meeting criteria for normal delivery. 5. Able to cooperate with procedures: conscious and able to change positions as required. 6. Fully informed about the clinical trial, voluntarily agrees to participate, and signs informed consent. 7. All parturients have no contraindications to anesthesia prior to the procedure, no history of opioid allergy, no pregnancy-related diseases, and no mental disorders.
Exclusion criteria
Exclusion criteria: 1. Infection at the puncture site; 2. Presence of blood disorders; 3. History of allergy to the investigational drug; 4. Presence of neurological disorders; 5. Unable to communicate normally with the investigator; 6. Individuals with psychological or psychiatric disorders; 7. History of long-term opioid use; 8. Patients judged to lack consent capacity; 9. Participation in other clinical trials recently; 10. Known allergy to a2 receptor agonists;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| maternal cooperation;Postpartum Depression; | — |
Secondary
| Measure | Time frame |
|---|---|
| PCEA demand presses and total analgesic consumption;Pain intensity and sedation level;Labor progress of parturients;Degree of neonatal asphyxia and resuscitation requirements;Intraoperative and postoperative adverse events; | — |
Countries
China
Contacts
Public ContactYang Heng
Hefei First People's Hospital
Outcome results
None listed