Recurrent Pregnancy Loss
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Have experienced two or more consecutive pregnancy losses before 28 weeks of gestation with the same partner, including biochemical pregnancies. 2.Both partners have a normal chromosomal karyotype; 3.The pregnant woman has no history of allergies or congenital anomalies; 4.Have normal liver function and have not used medications with potential adverse effects on fetal development such as oral contraceptives, anticoagulants, or fibrinolytics within the past three months.
Exclusion criteria
Exclusion criteria: 1.Cases with genital tract infections; 2.Uterine anomalies; 3.Routine examination indicates abnormal semen parameters in the male partner; 4.Experience severe adverse reactions during the treatment period;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Environmental factors in the tropical region of Hainan;Ultrasound examination data;Psychological assessment scales;Metabolomics;Anti-Xa activity;Thrombophilia-related gene polymorphisms; | — |
Countries
China
Contacts
Hainan General Hospital