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Efficacy and Cost-Effectiveness Analysis of Normal Saline Lock versus Heparinized Saline Lock for the Maintenance of Implantable Venous Access Ports (IVAP) Placed via the Internal Jugular/Subclavian Vein:Implications for DRG-Based Payment

Efficacy and Cost-Effectiveness Analysis of Normal Saline Lock versus Heparinized Saline Lock for the Maintenance of Implantable Venous Access Ports (IVAP) Placed via the Internal Jugular/Subclavian Vein:Implications for DRG-Based Payment

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600123617
Enrollment
Unknown
Registered
2026-04-28
Start date
2026-04-28
Completion date
Unknown
Last updated
2026-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Port Maintenance

Interventions

Heparin?saline group:None

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Successful implantation of IVAP via the internal jugular or subclavian vein; 2.Totally implantable venous access port; 3.Patients who have undergone continuous maintenance for 2 or more times; 4.Type of locking solution (heparin saline or normal saline) clearly recorded in medical/nursing documentation and relatively consistent (e.g., >90% of maintenance uses the same locking solution); 5.Age >= 18 years; 6.Patients undergoing maintenance in outpatient settings during the interval period; 7.No thrombosis detected by ultrasound before catheterization.

Exclusion criteria

Exclusion criteria: 1.Patients with severe hematological diseases; 2.Mixed or frequently changed types of locking solution; 3.Patients with severe coagulation disorders (e.g., active disseminated intravascular coagulation) or on long-term therapeutic anticoagulation; 4.Catheter removal due to catheter-related thrombosis (CRT) or catheter-related bloodstream infection (CRBSI) during the study period; 5.Presence of pinch-off syndrome, catheter rupture, no blood return on.

Design outcomes

Primary

MeasureTime frame
Catheter occlusion rate;

Secondary

MeasureTime frame
Catheter-related thrombosis (CRT);Catheter-related bloodstream infection (CLABSI);Local infection;Catheter displacement;

Countries

China

Contacts

Public ContactZerong Xie

West China Hospital of Sichuan University

329556349@QQ.com+86 138 8060 0809

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 7, 2026