Brain-heart co-occurring diseases
Conditions
Interventions
High-Risk Group for Riganosin Stress Echocardiography:None
Low-Risk Group for Riganosin Stress Echocardiography:None
Sponsors
Beijing Tiantan Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
45 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 45–80 years; 2. Meet the criteria for "high-risk patients with coexisting cerebrovascular and cardiovascular disease" (must satisfy all 3 criteria): (1) Cardiovascular disease: 1) Coronary artery disease (history of myocardial infarction >3 months, PCI, or CABG) or ST-T changes on resting ECG + positive exercise test; 2) Borderline cardiac function (LVEF 40%–50% or NT-proBNP 200–1,000 pg/mL); (2) Cerebrovascular disease: 1) Ischemic stroke/TIA > 3 months (mRS = 70% (asymptomatic); (3) Diabetes; (4) Cerebral small vessel disease (e.g., lacunar infarction); (5) Surgical risk: Elective non-cardiac surgery (carotid endarterectomy/major abdominal surgery/orthopedic/urological/thoracic surgery) expected to last >1 hour 3. ASA classification II–IV; 4. Undergo Riganosin stress echocardiography; 5. Sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Data unavailable; 2. Unable to complete follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| major adverse cardiovascular and cerebral events (MACCE) at 30 days post-surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| myocardial injury after non-cardiac surgery (MINS); | — |
Countries
China
Contacts
Public ContactYu Yun
Beijing Tiantan Hospital, Capital Medical University
Outcome results
None listed