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A Retrospective Analysis of Immune Checkpoint Inhibitor Therapy in Patients Aged 75 and Above with Advanced Non-small Cell Lung Cancer

A Retrospective Analysis of Immune Checkpoint Inhibitor Therapy in Patients Aged 75 and Above with Advanced Non-small Cell Lung Cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600123603
Enrollment
Unknown
Registered
2026-04-28
Start date
2026-05-01
Completion date
Unknown
Last updated
2026-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Advanced non-small cell lung cancer

Interventions

The monotherapy or combination therapy group of immune checkpoint inhibitors:None

Sponsors

Zhongshan People’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
75 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. The tissue pathology was diagnosed as NSCLC. 2. Those patients with clinical stage IIIB, IIIC or IV who are not suitable for surgery or radiotherapy; 3. Age 75 or above before receiving first-line treatment. 4. The first-line treatment options are chemotherapy or receiving adjuvant chemotherapy for more than half a year, and no immunotherapy has been used previously.

Exclusion criteria

Exclusion criteria: 1. Combine history of other types of cancer. 2. There is a lack of effective information for evaluating the efficacy and conducting follow-up. 3. Patients with incomplete data. 4. Patients who have undergone first-line systemic treatment for epidermal growth factor receptor gene mutations (EGFR) and anaplastic lymphoma kinase (ALK) rearrangement, or who received first-line systemic treatment with molecular targeted drugs (excluding anti-angiogenic drug therapy), were excluded.

Design outcomes

Primary

MeasureTime frame
Progression-free survival period;Overall survival period;

Countries

China

Contacts

Public ContactJunkai Zhang

Zhongshan People’s Hospital

jacob_zsrmyy@126.com+86 760 89880396

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 7, 2026