esophageal cancer
Conditions
Interventions
Group A (FiO2 100%), :FiO2 100%
Group B (FiO2 80%):FiO2 80%
Group C (FiO2 60%):FiO2 60%
Sponsors
The Second Affiliated Hospital of Air Force Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age range from 18 to 75 years old; 2. Diagnosed with esophageal cancer through pathology, planning to undergo minimally invasive esophageal cancer radical surgery (such as thoracoscopic assistance); 3. American Society of Anesthesiologists (ASA) grades I-III; 4. Body mass index (BMI) 18-28 kg/m ²; 5. The preoperative lung function test was basically normal.
Exclusion criteria
Exclusion criteria: 1. Patients who already have severe lung diseases (such as severe COPD, interstitial lung disease, pulmonary arterial hypertension) or require long-term home oxygen therapy before surgery; 2. Combined severe heart, liver, and kidney dysfunction (such as NYHA heart function grade III-IV); 3. Patients who require emergency surgery, severe pleural adhesions, or are expected to have difficulty in surgery or need to undergo thoracotomy; 4. Preoperative identification of difficult airways; 5. Those who do not cooperate with the research plan or refuse to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| atelectasis; | — |
Secondary
| Measure | Time frame |
|---|---|
| oxidative stress;blood gas analysis;Postoperative mechanical ventilation time; | — |
Countries
China
Contacts
Public ContactGao Changjun
The Second Affiliated Hospital of Air Force Medical University
Outcome results
None listed