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The Efficacy and Safety of Xenogeneic Collagen Matrix for Root Coverage in Thin Gingival Biotype Patients

The Efficacy and Safety of Xenogeneic Collagen Matrix (Fibro-Gide®) for Root Coverage in Thin Gingival Biotype Patients

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600123585
Enrollment
Unknown
Registered
2026-04-28
Start date
2026-04-28
Completion date
Unknown
Last updated
2026-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

RT I or II type gingival recession

Interventions

Test group:collagen matrix transplantation

Sponsors

Peking University Shenzhen Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 18 and 50, with no gender restrictions; 2. RT Type I or Type II gingival recession; 3. Thin gingival biotype; 4. Having completed periodontal initial therapy; 5. All participants using the same oral hygiene tools after oral hygiene instruction; 6. Patients exhibiting high compliance; 7. Patients agreeing to participate in this clinical study, voluntarily signing the informed consent form, and agreeing to participate in all visits, examinations, and treatments as required by the study protocol;

Exclusion criteria

Exclusion criteria: 1. Known allergy to the components of the intervention measures; 2. Using medications that may interfere with the healing process and cause gingival hyperplasia; 3. Pregnant or lactating women; 4. Active infection; 5. Patients with uncontrollable systemic diseases that may affect the surgical process and wound healing; 6. Participated in other clinical trials within the past 3 months.

Design outcomes

Primary

MeasureTime frame
root coverage;

Secondary

MeasureTime frame
width of keratinized gingiva;complication;patient aesthetic satisfaction;gingival thickness;pink aesthetic score;mucosal scar;

Countries

China

Contacts

Public ContactJiang Shaoyun

Peking University Shenzhen Hospital

jiangshaoyun11@126.com+86 755 83923333

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 7, 2026