Tic Disorders
Conditions
Interventions
Intervention Group:transcranial magnetic stimulation,TMS
Sham-Controlled Observation Group:pseudo-stimulation
Sponsors
Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
5 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1.Children and adolescents aged 5 to 18 years; 2.Meets DSM-5 diagnostic criteria for Tic Disorders (TDs) with normal EEG findings; 3.No prior treatment received for TDs; 4.Full-scale intelligence quotient (FIQ) =70 on the Wechsler Intelligence Scale for Children-Revised (WISC-R);
Exclusion criteria
Exclusion criteria: 1.WISC-R Full-Scale Intelligence Quotient (FIQ) 2mm during fMRI scanning, including both translational movement (TM) and rotational movement (RM); 4.Any other neurological or psychiatric conditions, including but not limited to autism spectrum disorder (ASD), epilepsy, obsessive-compulsive disorder (OCD), etc; 5.Previous head trauma ,Neurological diseases ,Major systemic illnesses;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tic Severity;Changes in fMRI brain region activity and functional connectivity; | — |
Countries
China
Contacts
Public ContactMa Jun
Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed