Chronic obstructive pulmonary disease, COPD
Conditions
Interventions
HFNC group:HFNC Treatment
NIV group:Noninvasive ventilation (NIV) was used
Sponsors
Affiliated Hospital of Jiangnan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Meets the diagnostic criteria for acute exacerbation of chronic obstructive pulmonary disease (AECOPD) accompanied by type II respiratory failure; (2) The clinical condition cannot be improved by relying solely on low-flow nasal cannula oxygen inhalation; (3) Age range: 18 - 80 years old, gender not restricted; (4) Voluntary to receive treatment and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with airflow limitation caused by asthma, bronchiectasis, or pulmonary fibrosis; (2) Those who have undergone lung transplantation or lung resection; (3) Those with severe hypertension, heart failure, arrhythmia, diabetes, primary heart, liver, kidney, blood, or neurological symptoms that are poorly controlled; (4) Patients with lung tumors, malignant tumors (within <5 years from the initial diagnosis, or with recurrence or metastasis confirmed by imaging or tumor markers, or undergoing radiotherapy, chemotherapy, targeted therapy, or immunotherapy, etc.); (5) Pregnant women, women planning to conceive, or lactating women; (6) Patients considered ineligible by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood gas analysis;Chest CT; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sputum culture;Blood inflammatory indicators, liver and kidney functions, myocardial enzymes, etc.;Pulmonary function; | — |
Countries
China
Contacts
Public ContactZuo Zhitong
Affiliated Hospital of Jiangnan University
Outcome results
None listed