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Cancelled by the investigator Clinical efficacy of hyperbaric oxygen combined with canulated screws in the treatment of displaced femoral neck fractures

Clinical Efficacy of Early Non-invasive Intervention with Hyperbaric Oxygen, rhBMP-2 Combined with Denosumab in Femoral Neck Fracture Patients Undergoing Internal Fixation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600123556
Enrollment
Unknown
Registered
2026-04-28
Start date
2026-04-29
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

femoral neck fractures

Interventions

Hyperbaric oxygen and bone morphogenetic protein-2 treatment:None
Early treatment with hyperbaric oxygen and bone morphogenetic protein-2 combined with denosumab:None

Sponsors

Hebei Provincial Department of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Aged 18–60 years; 2. Unilateral femoral neck fracture 3. Time from injury less than 2 weeks;4.No previous history of femoral neck fracture.

Exclusion criteria

Exclusion criteria: 1. Old femoral neck fracture; 2. Pathological fracture; 3. Patients with rheumatoid arthritis, congenital hip dysplasia, or avascular necrosis of the femoral head; 4. Patients with other severe metabolic diseases; 5. Long-term alcohol abusers or steroid users.

Design outcomes

Primary

MeasureTime frame
Fracture healing rate;Visual Analogue Scale for pain;—

Secondary

MeasureTime frame
Femoral head necrosis rate;Non-union rate of fractures;Harris Hip Score ;—

Countries

China

Contacts

Public ContactZhiyong Li

The Third Hospital of Hebei Medical University

38000491@hebmu.edu.cn+86 185 3311 2328

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 10, 2026