Gallbladder Cholesterol Stones
Conditions
Interventions
Acupoint Catgut Embedding + UDCA Group:Acupoint catgut embedding with PGLA absorbable sutures at Yanglingquan, Danshu, Riyue, and Gallbladder point, deep implantation, once every 2 weeks for 4 session
Ursodeoxycholic acid (UDCA): 10 mg/kg/day, oral nightly, for 12 weeks
Acupuncture + UDCA Group:Acupuncture at Yanglingquan, Danshu, Riyue, and Gallbladder point with superficial puncture (conventional acupuncture), once every 2 weeks for 4 sessions
Sponsors
The Third Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18–65 years; 2. Diagnosed with gallbladder cholesterol stones by ultrasonography (diameter = 10 mm); 3. Reduced gallbladder contractile function (GBEF = 35%); 4. Patency of the cystic duct; 5. No recent acute complications; 6. Voluntary signing of informed consent.
Exclusion criteria
Exclusion criteria: 1. Gallbladder pigment stones; 2. Acute cholecystitis or cholangitis; 3. Non-functioning gallbladder or severe hypokinesia; 4. Gallbladder atrophy or wall thickness > 3 mm; 5. Complete biliary obstruction; 6. Hypersensitivity to ursodeoxycholic acid (UDCA) components or absorbable materials; 7. Severe hepatic or renal dysfunction; 8. Pregnancy or lactation; 9. Contraindications related to catgut embedding (e.g., infection or ulceration at the planned embedding site; bleeding tendency).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete stone dissolution rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Partial stone dissolution rate;Gallbladder function recovery;Clinical symptom relief;Quality of life improvement; | — |
Countries
China
Contacts
Public ContactXiong Zhiyong
The Third Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed