acquired benign esophageal-respiratory fistulas
Conditions
Interventions
Group B (Fistula orifice maximum diameter 1-2 cm):Endoscopic submucosal injection of autologous platelet-rich plasma and/or Over-The-Scope Clip (OTSC) closure procedure
Group A (fistula orifice maximum diameter < 1 cm):Endoscopic submucosal injection of autologous platelet-rich plasma and/or Over-The-Scope Clip (OTSC) closure procedure
Sponsors
Emergency General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 to 80 years were included. 2. Patients with a confirmed diagnosis of acquired benign esophageal-respiratory fistulas (ABERFs) by gastroscopy, bronchoscopy, or imaging studies were included.
Exclusion criteria
Exclusion criteria: 1. Fistula orifice >20 mm in maximum diameter; 2. Coagulopathy or bleeding disorders; 3. Severe cardiac/pulmonary dysfunction; 4. Contraindication to or refusal of endoscopic OTSC/auto-PRP therapy; 5. Thoracic radiotherapy or chemotherapy within the last 2 months; 6. Investigator’s judgment of unsuitability.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the clinical healing rate of endoscopic treatment for acquired benign esophageal-respiratory fistulas; | — |
Secondary
| Measure | Time frame |
|---|---|
| the incidence of adverse reactions to endoscopic treatment for acquired benign esophageal-respiratory fistulas;the mean length of hospital stay and cost associated with endoscopic treatment for acquired benign esophageal-respiratory fistulas;the technical success rate of endoscopic treatment for acquired benign esophageal-respiratory fistulas; | — |
Countries
China
Contacts
Public ContactXiaochuan Liu
Emergency General Hospital
Outcome results
None listed