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Effects of Integrated Multisensory Environmental Stimulation on Consciousness Recovery and Brain Network Mechanisms in Minimally Conscious State Patients

Effects of Integrated Multisensory Environmental Stimulation on Consciousness Recovery and Brain Network Mechanisms in Minimally Conscious State Patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600123505
Enrollment
Unknown
Registered
2026-04-27
Start date
2026-05-01
Completion date
Unknown
Last updated
2026-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disorders of Consciousness

Interventions

Experimental Group:Multisensory Environmental Stimulation

Sponsors

Shanghai Yangzhi rehabilitation hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Stroke with concomitant disorders of consciousness for =28 days, confirmed by cranial CT or MRI examination; 2.Meet the diagnostic criteria for minimally conscious state (MCS) as recommended by the Aspen Neurobehavioral Conference Workgroup (ANCW; 3.Vital signs are stable; 4.Informed consent obtained from the family members of all enrolled patients;

Exclusion criteria

Exclusion criteria: 1.Disorders of consciousness caused by other etiologies; 2.Active intracranial hemorrhage; 3.History of epilepsy; 4.Patients with locked-in syndrome; 5.Severe vital organ failure involving the heart, liver, kidneys, etc. 6.Inability to cooperate with examinations or tests;

Design outcomes

Primary

MeasureTime frame
level of consciousness;

Secondary

MeasureTime frame
Brain stem auditory evoked potential;degree of brain function impairment;cognitive function;oxyhemoglobin concentration;

Countries

China

Contacts

Public ContactHe Ting

Shanghai Yangzhi rehabilitation hospital

81803004@qq.com+86 137 6456 4906

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 7, 2026