Postpartum hemorrhage
Conditions
Interventions
Experimental group:1g intravenous injection of tranexamic acid after umbilical cord clamping(Dissolve in 100mL physiological saline, drip time >= 10 minutes)
Control group:Immediately after umbilical cord clamping, 10 units of oxytocin+1ml of cabetocin (100 µ g) were injected intravenously
Sponsors
Hangzhou First People's Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Pregnant women with twin pregnancies who undergo regular prenatal check ups and plan to give birth at our hospital; 2. At 36-38 weeks of gestation, choose a cesarean section 3. Age range: 20-45 years old; 4. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Combined coagulation dysfunction, history of thrombotic diseases, or hematological disorders; 2. Serious pregnancy complications (such as severe pre eclampsia and poor control of diabetes in pregnancy); 3. Placental factors such as placenta previa and placental implantation that are clearly associated with an increased risk of PPH; 4. Severe heart, liver, and kidney dysfunction; 5. Individuals who are allergic to the research drugs (tranexamic acid, carbidogrel).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative blood loss;Postoperative 24-hour bleeding volume;Does it cause postpartum bleeding; | — |
Secondary
| Measure | Time frame |
|---|---|
| Usage of additional uterine contraction agents;Other hemostatic measures;Blood transfusion situation; | — |
Countries
China
Contacts
Public ContactDong Xiao
Hangzhou First People's Hospital
Outcome results
None listed