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Comparison of the application effect of hydrocodone or ketamine combined with ropivacaine for paravertebral nerve block analgesia in lung cancer patients

Comparison of the application effect of hydrocodone or ketamine combined with ropivacaine for paravertebral nerve block analgesia in lung cancer patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600123487
Enrollment
Unknown
Registered
2026-04-27
Start date
2026-05-11
Completion date
Unknown
Last updated
2026-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain in lung cancer patients

Interventions

Sponsors

Shifang People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. ASA levels I-III 2. Age range from 20 to 80 years old 3. Weight 45-80 kg 4. Ethical compliance and informed consent.

Exclusion criteria

Exclusion criteria: 1. Preoperative addiction to painkillers 2. Mental and neurological disorders 3. History of asthma 4. Individuals with severe cardiopulmonary dysfunction and liver and kidney dysfunction 5. Patients who refuse to cooperate with the trial 6. Skin lesions at the puncture site, history of severe vomiting or motion sickness, and communication difficulties.

Design outcomes

Primary

MeasureTime frame
VAS score;BCS score;Number of compressions for self controlled pain relief;CRP;IL-6;TNF-a;

Secondary

MeasureTime frame
First time of getting out of bed activity after surgery;Adverse reactions (observed and recorded within 48 hours after operation: nausea and vomiting, dizziness and lethargy, skin pruritus, urinary retention, respiratory depression, local anesthetic reaction, hallucination and irritability, local discomfort after puncture.);

Countries

China

Contacts

Public ContactLin Zeng

Shifang People's Hospital

343329636@qq.com+86 152 8147 0503

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 7, 2026