Long-term bed rest resulting from post-stroke neurological dysfunction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years; 2.Diagnosis of acute stroke (including cerebral infarction, intracerebral hemorrhage, and subarachnoid hemorrhage) confirmed by cranial CT or MRI, with persistent bed rest due to neurological dysfunction; 3.At least one documented standardized rehabilitation assessment or treatment during hospitalization; 4.Complete data on key time points (onset of bed rest, initiation of rehabilitation, end of observation) and key outcome indicators (color Doppler ultrasound of both lower extremities);
Exclusion criteria
Exclusion criteria: 1.Bedridden prior to the current stroke or with a documented history of lower extremity deep vein thrombosis (DVT); 2.Window period exclusion: DVT confirmed by imaging within 7 days after becoming bedridden, or presence of typical DVT symptoms without ultrasound examination; 3.Receipt of any form of anticoagulant therapy (including prophylactic and therapeutic doses) during the bed rest period; 4.Presence of active malignancy or known hereditary thrombophilia (e.g., protein C/S deficiency, antiphospholipid syndrome, etc.); 5.Presence of lower extremity varicose veins or history of prior lower extremity vascular surgery; 6.Significant progression of stroke or receipt of new neurosurgical or interventional procedures within 7 days after becoming bedridden, resulting in a fundamental change in treatment plan; 7.Cases with > 20% missing key clinical data;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Deep vein thrombosis of lower extremities; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of pulmonary embolism (PE);Clinical outcome (90-day mortality rate);Time to ambulation;Adverse events (including hemodynamic fluctuations related to rehabilitation, falls/falls from bed, new bleeding events); | — |
Countries
China
Contacts
Quzhou People Hospital