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Association Analysis of Rehabilitation Intervention in Bedridden Stroke Patients and the Incidence of Lower Extremity Deep Vein Thrombosis, and the Development and Validation of a Risk Prediction Model: A Retrospective Cohort Study

Association Analysis of Rehabilitation Intervention in Bedridden Stroke Patients and the Incidence of Lower Extremity Deep Vein Thrombosis, and the Development and Validation of a Risk Prediction Model: A Retrospective Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600123468
Enrollment
Unknown
Registered
2026-04-27
Start date
2026-05-20
Completion date
Unknown
Last updated
2026-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Long-term bed rest resulting from post-stroke neurological dysfunction

Interventions

Observation Group:None

Sponsors

Quzhou People Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >= 18 years; 2.Diagnosis of acute stroke (including cerebral infarction, intracerebral hemorrhage, and subarachnoid hemorrhage) confirmed by cranial CT or MRI, with persistent bed rest due to neurological dysfunction; 3.At least one documented standardized rehabilitation assessment or treatment during hospitalization; 4.Complete data on key time points (onset of bed rest, initiation of rehabilitation, end of observation) and key outcome indicators (color Doppler ultrasound of both lower extremities);

Exclusion criteria

Exclusion criteria: 1.Bedridden prior to the current stroke or with a documented history of lower extremity deep vein thrombosis (DVT); 2.Window period exclusion: DVT confirmed by imaging within 7 days after becoming bedridden, or presence of typical DVT symptoms without ultrasound examination; 3.Receipt of any form of anticoagulant therapy (including prophylactic and therapeutic doses) during the bed rest period; 4.Presence of active malignancy or known hereditary thrombophilia (e.g., protein C/S deficiency, antiphospholipid syndrome, etc.); 5.Presence of lower extremity varicose veins or history of prior lower extremity vascular surgery; 6.Significant progression of stroke or receipt of new neurosurgical or interventional procedures within 7 days after becoming bedridden, resulting in a fundamental change in treatment plan; 7.Cases with > 20% missing key clinical data;

Design outcomes

Primary

MeasureTime frame
Deep vein thrombosis of lower extremities;

Secondary

MeasureTime frame
Incidence of pulmonary embolism (PE);Clinical outcome (90-day mortality rate);Time to ambulation;Adverse events (including hemodynamic fluctuations related to rehabilitation, falls/falls from bed, new bleeding events);

Countries

China

Contacts

Public ContactLi Boyi

Quzhou People Hospital

2510419737@qq.com+86 570 8031216

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 7, 2026