Postoperative delirium
Conditions
Interventions
Intervention group:40 Hz binaural beat auditory intervention will be administered starting when the patient is awake and cooperative in the PACU, until 24:00 on the 3rd postoperative day. Specific pro
Sponsors
The First Affiliated Hospital of Hebei North University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >= 65 years, regardless of gender; 2. Scheduled for elective hip surgery under general anesthesia (including femoral neck fracture replacement, intertrochanteric fracture internal fixation, etc.); 3. American Society of Anesthesiologists (ASA) physical status classification II–IV; 4. Preoperative Mini-Mental State Examination (MMSE) score >= 24, with no confirmed dementia or severe cognitive impairment; 5. No severe hearing impairment, tympanic membrane perforation, otitis media, or hyperacusis, and able to cooperate with intervention using Bluetooth earphones; 6. The patient or legal representative fully understands the study protocol and voluntarily provides written informed consent; 7. Expected to complete at least 72 hours of postoperative observation and assessment, with no likelihood of immediate postoperative ICU transfer or long-term mechanical ventilation.
Exclusion criteria
Exclusion criteria: Preoperatively diagnosed with severe cognitive impairment such as dementia, Alzheimer’s disease, Parkinson’s disease, or with a history of psychiatric disorders; 2. Complicated with organic central nervous system lesions (e.g., cerebral infarction, cerebral hemorrhage, intracranial tumor, hydrocephalus, etc.); 3. Presence of severe hearing impairment, congenital auditory abnormalities, inability to tolerate wearing earphones, or hypersensitivity to acoustic stimulation; 4. Immediate postoperative transfer to intensive care unit (ICU), requirement of mechanical ventilation for more than 24 hours, and inability to complete intervention and assessment; 5. Complicated with severe hepatic or renal insufficiency, malignant tumor, severe infection, autoimmune disease, etc.; 6. Participation in other clinical studies within the past 3 months; 7. Refusal to participate in this study by the patient or family members, or inability to cooperate and complete the entire follow-up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative delirium (POD).; | — |
Countries
China
Contacts
Public ContactSun Xiaojia
The First Affiliated Hospital of Hebei North University
Outcome results
None listed