Colorectal malignant tumors/Colon cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Diagnostic criteria for diabetes: "three excesses and one deficiency" symptoms of polyuria, polydipsia, polyphagia, and weight loss along with hyperglycemia; Glycated hemoglobin >= 6.5% (Testing should be conducted in a laboratory using NGSP certification and DCCT standardized testing methods); or fasting blood glucose >= 7.0 mmol/L (Fasting refers to at least 8 hours without calorie intake); or 2-hour blood glucose after OGTT >= 11.1 mmol/L (As stated by WHO, OGTT test refers to the 75g anhydrous glucose load test); or random blood glucose >= 11.1 mmol/L (Random refers to any time within a day, disregarding the time since the last meal). Diagnosis requires abnormal test results from two or more (glycated hemoglobin and fasting blood glucose or 2-hour blood glucose after OGTT or random blood glucose) or obtained at two different time points. 2. Diagnosis of colorectal cancer: Confirmed by preoperative biopsy and postoperative pathological examination. TNM staging follows the 8th edition of AJCC colorectal cancer staging. 3. Age >= 18 years old; 4. Complete clinical, pathological, and follow-up data.
Exclusion criteria
Exclusion criteria: 1. combined with other malignant tumors; 2. death within 30 days after operation; 3. lost to follow-up or incomplete follow-up information; 4. complicated with severe heart, liver and kidney dysfunction or infectious diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival(OS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Laboratory indicators (CEA, CA19-9, white blood cell count, NLR, PLR, etc.);Basic information of patients hospitalized (age, sex, smoking history, drinking history, BMI, etc.);Treatment information (operation mode, chemotherapy regimen, radiotherapy);Tumor characteristics (location, TNM stage, differentiation, lymph node metastasis, etc.);Diabetes related (diabetes duration, treatment methods, relevant monitoring indicators - fasting blood glucose / glycated hemoglobin, etc.); | — |
Countries
China
Contacts
The First Affiliated Hospital of the Baotou Medical College of Inner Mongolia University of Science and Technology