FindTrial
Sign In

Increase the effect of MAP on renal hemodynamics, microcirculation and oxygen metabolism in patients with septic shock

Increase the effect of MAP on renal hemodynamics, microcirculation and oxygen metabolism in patients with septic shock

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600123397
Enrollment
Unknown
Registered
2026-04-26
Start date
2025-07-15
Completion date
Unknown
Last updated
2026-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

septic shock

Interventions

Test group:The dose of norepinephrine was adjusted to increase MAP to 65-75mmHg, 75-85mmHg, and 85-95mmHg respectively

Sponsors

Northern Jiangsu People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients with septic shock;

Exclusion criteria

Exclusion criteria: 1. Under the age of 18; 2. Pregnant and lactating women; 3. Those with active bleeding; 4. Those whose MAP remains elevated and stable within 1 hour after an increase in the dose of norepinephrine; 5. Chronic renal failure; 6. Urinary calculus; 7. Renal arteries cannot be imaged.

Design outcomes

Primary

MeasureTime frame
Renal blood flow;—

Secondary

MeasureTime frame
Heart Rate;renal artery resistance index;Renal Artery Pulsatility Index;Renal Artery Peak Systolic Velocity;Renal Artery End-Diastolic Velocity;S/D;Renal Artery Diameter;—

Countries

China

Contacts

Public ContactZheng Ruiqiang

Northern Jiangsu People's Hospital

rqzh7@yahoo.com.cn+86 514 8737004

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 22, 2026