Smear-negative pulmonary tuberculosis
Conditions
Interventions
Gold Standard:Sputum specimens were negative by smear, culture, and molecular testing, but the clinical symptoms were consistent with pulmonary tuberculosis.
Index test:For multiple specimen types including sputum, bronchoalveolar lavage fluid, and pathological tissue, molecular testing was performed as follows: Fluorescence quantitative PCR was used to de
Sponsors
Beijing Chest Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
1 Years to 90 Years
Inclusion criteria
Inclusion criteria: Retrospective cohort: 1. Patients with pulmonary tuberculosis who are unable to produce sputum or have negative results on sputum smear, culture, and molecular tests. Prospective cohort: 1.Patients who agree to participate in this project and sign the informed consent form; 2. Patients with pulmonary tuberculosis who are unable to produce sputum or have negative results on sputum smear and molecular tests.
Exclusion criteria
Exclusion criteria: Retrospective cohort: 1. Patients deemed by the investigator to be unsuitable for participation in this study. Prospective cohort: 1.Patients with smear-positive pulmonary tuberculosis (positive on sputum smear, molecular test, or culture); 2. Patients deemed by the investigator to be unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Multi-sample Molecular Test Results; | — |
Countries
China
Contacts
Public ContactChe Nanying
Beijing Chest Hospital, Capital Medical University
Outcome results
None listed