Symmetrical weakness of the limbs and respiratory muscle weakness
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age between 18 and 80 years old; 2. Meets the diagnostic criteria for ICU-acquired weakness as stipulated by the Medical Research Council; 3. ICU stay duration >= 48 hours, mechanical ventilation duration >= 24 hours; 4. Self-care ability was normal one week before admission to the ICU; 5. Stable vital signs and clear consciousness; 6. Obtained informed consent from the patient or the patient's family.
Exclusion criteria
Exclusion criteria: 1. There are early activity contraindications such as limb movement disorders, limb disability or loss, fractures, etc.; 2. There are contraindications for chest physical therapy due to acute myocardial infarction, pulmonary embolism, etc.; 3. There is severe acute respiratory distress syndrome; 4. Pregnant women, patients with mental disorders; those with neurological diseases or organic brain damage, and those in a deep coma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FEV1, FEV1%, FEV1/FEV1 (%); | — |
Secondary
| Measure | Time frame |
|---|---|
| diaphragm activity;Oxygenation index;Barthel Index assessment; | — |
Countries
China
Contacts
First Hospital Of Nanping