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To investigate the effects of Compound Chamomile and Lidocaine Hydrochloride Gel as an endotracheal tube lubricant on perioperative comfort in patients undergoing gynecological laparoscopic surgery.

Compound Chamomile and Lidocaine Hydrochloride Gel for Perioperative Comfort Study in Patients Undergoing Gynecological Laparoscopy and Endotracheal Intubation

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600123379
Enrollment
Unknown
Registered
2026-04-26
Start date
2025-07-02
Completion date
Unknown
Last updated
2026-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complications of endotracheal intubation

Interventions

Compound Lidocaine Cream Group:Lubrication of the endotracheal tube with Compound Lidocaine Cream
Dyclonine Mucilage Group:Lubrication of the endotracheal tube with Dyclonine Mucilage
Compound Chamomile and Lidocaine Hydrochloride Gel Group:Lubrication of the endotracheal tube with Compound Chamomile and Lidocaine Hydrochloride Gel
Paraffin Oil Group:Lubrication of the endotracheal tube with paraffin oil.

Sponsors

Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: 1.Female patients aged 18 to 64 years; 2.Ability to verbally comprehend all study procedures and willingness to comply with all requirements throughout the research; 3.ASA I-II; 4.Scheduled to undergo general anesthesia with endotracheal intubation;

Exclusion criteria

Exclusion criteria: 1.Allergy to local anesthetics; 2.History of smoking, asthma, chronic pharyngitis, or gastroesophageal reflux disease; 3.Presence of sore throat, hoarseness, respiratory tract infection, or oral ulcers within the past week; 4.Congenital or acquired upper respiratory tract abnormalities; 5.Coagulation disorders; 6.History of difficult intubation; 7.Anticipated difficult airway conditions, such as Mallampati score > II; 8.Congenital or idiopathic methemoglobinemia;

Design outcomes

Primary

MeasureTime frame
Complications of endotracheal intubation;

Secondary

MeasureTime frame
postoperative hypertension;Immediate stress response upon extubation;Postoperative body temperature;satisfaction survey;postoperation pain;sleep quality;postoperative nausea and vomiting;

Countries

China

Contacts

Public ContactXiaoxia Wang

Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region

734578771@qq.com+86 771 2860618

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 7, 2026