Systemic lupus erythematosus
Conditions
Interventions
Sponsors
First Affiliated Hospital of Kunming Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.All subjects were SLE patients recruited from each center between January 2025 and December 2027 who voluntarily signed informed consent forms; 2.Aged 18–65 years, either sex; 3.Diagnosis consistent with the 2012 Systemic Lupus International Collaborating Clinics (SLICC) classification criteria or the 2019 EULAR/ACR SLE classification criteria; 4.Clinically diagnosed with SLE for at least 12 weeks prior to enrollment; 5.Educational level of primary school or above, proficient in Mandarin Chinese with capacity to comprehend scale contents, and capable of completing the questionnaires.
Exclusion criteria
Exclusion criteria: 1.Diagnosed with schizophrenia, mental retardation, alcohol abuse, alcohol dependence, or other psychoactive substance dependence; 2.History of major organic brain diseases, including trauma, tumor, stroke, infection, contagious disease, epilepsy, or definite neurodegenerative disorders; 3.Comorbid with other autoimmune diseases meeting ACR classification criteria for rheumatoid arthritis, systemic sclerosis, Sjögren's syndrome (primary or secondary), other connective tissue diseases, or drug-induced SLE; 4.Patients with severe cardiac, hepatic, renal, or pulmonary insufficiency; 5.Women who are pregnant, lactating, or planning pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Systemic Lupus Erythematosus Disease Activity?Physician Global Assessment?Lupus Low Disease Activity State?Depression Scale ?Anxiety Scale?Cognitive Function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional Magnetic Resonance Imaging,Neuroelectrophysiological Examination;Somatic Symptom Scale; | — |
Countries
China
Contacts
Public Contactjianxu
First Affiliated Hospital of Kunming Medical University
Outcome results
None listed