Dentofacial deformity
Conditions
Interventions
Observation Group:None
Sponsors
The Affiliated Stomatology Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 30 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 years or older and 30 years or younger, regardless of gender; 2. Clinically diagnosed with skeletal Class III malocclusion accompanied by maxillary sagittal deficiency, and requiring surgical correction via LeFort I osteotomy with maxillary advancement.
Exclusion criteria
Exclusion criteria: 1. Patients with severe osseous deformities or bone defects caused by trauma, cleft lip/palate, tumors, etc; 2. Patients diagnosed preoperatively with intrasinus diseases such as sinusitis, cysts, or tumors; 3. Patients with systemic diseases (e.g., diabetes mellitus, autoimmune deficiency syndrome); 4. Patients with contraindications to orthognathic surgery; 5. Patients who refuse to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hematoxylin and Eosin staining results; | — |
Secondary
| Measure | Time frame |
|---|---|
| Flow Cytometry Identification Results;Real-time Fluorescence Quantitative Polymerase Chain Reaction Assay;Alkaline Phosphatase Activity Assay;Alizarin Red S Staining; | — |
Countries
China
Contacts
Public ContactXie Zhijian
The Affiliated Stomatology Hospital of Zhejiang University School of Medicine
Outcome results
None listed