Perioperative Glycemic Dysregulation in Liver Transplantation
Conditions
Interventions
Early postoperative infection group and non-infection group following liver transplantation:None
Sponsors
The Second Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients who underwent liver transplantation during the study period; 2. Patients had no clinical or laboratory evidence of infection for at least one week prior to transplantation; 3. Sufficient perioperative blood glucose records were available, including data for at least three days postoperatively; 4. Complete clinical data were available;
Exclusion criteria
Exclusion criteria: 1. Patients with evidence of infection or bacterial colonization within one week prior to transplantation; 2. Patients who died from non-infectious causes within one month after liver transplantation; 3. Patients undergoing repeat liver transplantation; 4. Patients with severely incomplete clinical data; 5. Patients who received extracorporeal membrane oxygenation (ECMO) support during the procedure;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall infection rate within 30 days postoperatively;Site of infection (abdominal cavity, lungs, bloodstream, surgical site, urinary tract, etc.);Severity grading of infection (simple infection, sepsis, septic shock);Blood glucose levels (overall and mean glucose values at different phases, peak levels);Glucose variability (standard deviation SD, coefficient of variation CV);In-hospital mortality rate;Delayed graft function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Reoperation due to infection;Prolonged intensive care unit (ICU) stay;Pathogen type (bacteria, fungi, particularly Candida species); | — |
Countries
China
Contacts
Public ContactGao Yingying
The Second Affiliated Hospital of Guangxi Medical University
Outcome results
None listed