Obstetric antiphospholipid syndrome (OAPS)
Conditions
Interventions
OAPS Group:None
Healthy maternal group:None
Sponsors
The international peace maternity and child health hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Maternal women who delivered live births and were hospitalized at the International Peace Maternity and Child Health Hospital, China Welfare Institute, between 2018 and 2024.
Exclusion criteria
Exclusion criteria: 1.Diagnosed with APS prior to pregnancy; 2.Patients with a history of thrombosis or pregnancy complicated by thrombosis; 3.History of smoking or alcohol consumption; 4.Use of medications during pregnancy that significantly affect maternal and infant outcomes; 5.History of major diseases such as severe organ lesions complicating pregnancy; 6.Patients with active infections including HBV, HCV, HIV, syphilis, or tuberculosis; 7.Patients undergoing induced labor due to family planning or personal requests; 8.Those who did not undergo routine prenatal examinations, resulting in incomplete data; 9.Multiple pregnancies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Coagulation function-related indicators (INR, APTT, TT, PT, fibrinogen concentration, D-dimer, FDP); | — |
Secondary
| Measure | Time frame |
|---|---|
| Complete Blood Count (Total Bile Acids, Red Blood Cells, Hemoglobin, Platelets);Pregnancy complications (Gestational Diabetes Mellitus, thyroid disorders, hypertensive disorders of pregnancy, eclampsia, anemia, Intrahepatic Cholestasis of Pregnancy);Pregnancy outcome(Postpartum hemorrhage?Neonatal weight?Amniotic fluid condition?Placental condition); | — |
Countries
China
Contacts
Public ContactJingjin Shi
The international peace maternity and child health hospital
Outcome results
None listed