None
Conditions
Interventions
Remimazolam group:Remimazolam
Propofol group:Propofol
Sponsors
The Second Xiangya Hospital, Central South University
Eligibility
Sex/Gender
All
Age
18 Years to 88 Years
Inclusion criteria
Inclusion criteria: 1. Age 18–88 years 2. ASA physical status I–III 3. BMI 18–28 kg/m^2 4. Patients scheduled for elective surgery under general anesthesia 5. Voluntary participation with written informed consent provided
Exclusion criteria
Exclusion criteria: 1: Allergy to benzodiazepines 2: Predicted difficult airway as assessed by the anesthesiologist 3: History of cardiopulmonary insufficiency, such as diagnosed coronary artery disease 4: Diagnosed psychiatric disorders, including depression, anxiety, or schizophrenia Substance abuse (e.g., drugs, alcohol, or psychoactive substances) 5: Markedly abnormal liver or renal function on laboratory testing 6: Structural abnormalities of the heart or lungs identified on imaging examinations 7: Refusal to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alpha-band spectral power;Delta-band spectral power;PSI andSEF values at different time points; | — |
Secondary
| Measure | Time frame |
|---|---|
| Alpha-band coherence;Comparison of vital signs during the monitoring period and the incidence of adverse events (AEs); | — |
Countries
China
Contacts
Public ContactHai-Ding Zou
The Second Xiangya Hospital, Central South University
Outcome results
None listed