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Study on Factors Associated With Early Recurrence and Patterns of Recurrence After Pancreatic Cancer Surgery

Risk Factors and Recurrence Patterns of Early Recurrence After Curative Resection for Pancreatic Cancer: A Retrospective Cohort and Case-Control Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600123325
Enrollment
Unknown
Registered
2026-04-24
Start date
2026-04-27
Completion date
Unknown
Last updated
2026-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pancreatic ductal adenocarcinoma

Interventions

Non-early recurrence group:None
Early recurrence group:None

Sponsors

Zhejiang Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >=18 years; 2. Postoperative pathological confirmation of pancreatic cancer, specifically pancreatic ductal adenocarcinoma (PDAC); 3. Underwent curative resection (including pancreaticoduodenectomy, distal pancreatectomy, total pancreatectomy, etc.), with a clearly documented date of surgery; 4. Available postoperative follow-up data sufficient to determine recurrence status (recurrence vs no recurrence) and key time points (date of recurrence or date of last follow-up); 5. Availability of key clinicopathological data, including at minimum T/N stage or lymph node status, tumor differentiation grade, and resection margin status;

Exclusion criteria

Exclusion criteria: 1. Perioperative death (e.g., death within 30 days after surgery ); 2. Documented distant metastasis (M1) before surgery; 3. Concurrent synchronous malignancies that may significantly affect prognostic assessment; 4. Missing key outcome data, including inability to determine the date of recurrence or the date of last follow-up; 5. Severe missingness of key pathological data that could not be supplemented;

Design outcomes

Primary

MeasureTime frame
Local recurrence time;

Secondary

MeasureTime frame
overal survival;Recurrence-free survival;microenvironment of tumor;

Countries

China

Contacts

Public ContactShi Lei

Zhejiang Provincial People's Hospital

shileihmu@163.com+86 571 85893638

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 7, 2026