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Effectiveness of high-frequency ultrasound-guided acupuncture of the sphenopalatine ganglion combined with heat-sensitive moxibustion in the treatment of perennial allergic rhinitis: a prospective, multicenter, randomized controlled trial

Effectiveness of high-frequency ultrasound-guided acupuncture of the sphenopalatine ganglion combined with heat-sensitive moxibustion in the treatment of perennial allergic rhinitis: a prospective, multicenter, randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600123324
Enrollment
Unknown
Registered
2026-04-24
Start date
2026-05-01
Completion date
Unknown
Last updated
2026-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

allergic rhinitis

Interventions

Intervention group:high-frequency ultrasound-guided sphenopalatine ganglion acupuncture combined with heat-sensitive moxibustion
Control group:Budesonide Nasal Spray therapy

Sponsors

The Second Affiliated Hospital of Nanchang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Participants meeting the diagnostic criteria, mainly those with moderate-to-severe perennial allergic rhinitis (AR). The Total Nasal Symptom Score (TNSS) was used as the primary defining criterion. TNSS is the sum of scores for 4 nasal symptoms, nasal obstruction, rhinorrhea, sneezing, and nasal itch, with each symptom rated on a scale of 0 (no symptom) to 4 (severe symptom). The total TNSS ranges from 0 to 16. Specifically, a TNSS of > 0 and 4 indicates moderate-to-severe AR. 2. Heat-sensitive moxibustion sensations were detected at points 1 cun superior, inferior, left and right to Yintang (EX-HN3). 3. Aged 18 to 65 years, regardless of gender;Voluntarily participated in this clinical observation and signed the informed consent form. 4. Able to comply with the physician’s treatment arrangements and coordinate with the treatment and follow-up procedures. 5. With clear consciousness, capable of accurately describing moxibustion sensations and cooperating with clinical operations. 6. The patient had normal consciousness, was able to accurately describe moxibustion sensations, and cooperated well during the procedure. 7. Voluntarily participated in the trial and signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Participants with severe concurrent diseases of the cardiovascular and cerebrovascular systems, liver, kidneys, hematopoietic system, or other major organs. 2. Participants with other nasal disorders, such as chronic rhinitis, sinusitis, or the like. 3. Participants with psychiatric disorders; pregnant or lactating women. 4. Participants with concurrent upper respiratory tract diseases, such as asthma, bronchitis, or others. 5. Participants with a history of needle syncope, moxibustion syncope, or rejection of acupuncture and moxibustion. 6. Participants intolerant to moxa smoke.

Design outcomes

Primary

MeasureTime frame
Total Nasal Symptom Score, TNSS;

Secondary

MeasureTime frame
Total Non-Nasal Symptom Score, TNNSS;Rhinoconjunctivitis Quality of Life Questionnaire, RQLQ;

Countries

China

Contacts

Public ContactXiong Jun

The Second Affiliated Hospital of Nanchang University

xiongjun196071@163.com+86 139 7005 4277

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 7, 2026