infertility
Conditions
Interventions
OOSP2 group:Fertilization medium and embryo culture medium supplemented with recombinant OOSP2 protein.
Empty group:Fertilization medium and embryo culture medium supplemented without recombinant OOSP2 protein.
Sponsors
Reproductive Medicine Center of the Sixth Affiliated Hospital of Sun Yan-Sen University
Eligibility
Sex/Gender
Female
Age
35 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Subjects aged between 35 and 45 undergoing IVF/ICSI in the Sixth Affiliated Hospital of Sun Yan-Sen University. 2. The number of oocytes retrieved >= 6. 3. Subjects and their guardians or husbands voluntarily signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with definite indications for or planning to undergo preimplantation genetic testing for structural rearrangements (PGT-SR); 2. Oocyte maturation disorder and/or surgical sperm retrieval; 3. Semen donors or oocytes donors;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| High-quality blastocyst rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Normal fertilization rate (2PN rate);Day 3 usable embryo rate;Day 3 high-quality embryo rate;Usable blastocyst rate; | — |
Countries
China
Contacts
Public ContactHaitao Zeng
Reproductive Medicine Center of the Sixth Affiliated Hospital of Sun Yan-Sen University
Outcome results
None listed