None
Conditions
Interventions
Group receiving neoadjuvant therapy prior to surgery:None
Group that did not receive neoadjuvant therapy prior to surgery:None
Sponsors
Affiliated Hospital of Guizhou Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. ASA classification =18 years; 3. Pathological diagnosis of breast cancer; 4. No severe visual or hearing impairments and able to read, capable of understanding and cooperating with neuropsychological tests; 5. Planned elective or limited-time breast cancer surgery under general anesthesia, with an expected surgery duration >=60 minutes; 6. Expected postoperative hospital stay of at least 3 days; 7. Patient voluntarily participates and signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients with intracranial abnormalities (central nervous system-related diseases) detected by cranial CT or MRI examination; 2.Patients with severe systemic diseases prior to surgery (e.g., respiratory system, circulatory system, severe liver or kidney dysfunction, etc.); 3.Patients with a history of psychiatric symptoms or diseases that preclude cooperation with cognitive assessment, or patients with dependence on psychotropic substances; 4.Patients with a history of alcohol or drug abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function 3 months post-surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| IL-6;IL-8;TNF-a; | — |
Countries
China
Contacts
Public ContactXiaohua Zou
Affiliated Hospital of Guizhou Medical University
Outcome results
None listed