cerebrovascular disease
Conditions
Interventions
Heparinization group:Systemic heparinisation following femoral artery sheath placement
No-heparinization group:No systemic heparinization was used after femoral artery sheathing, and unfractionated heparin was injected intravenously after sheathing
Sponsors
Shenzhen Hospital of Southern Medical Unversity
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Adult patients undergoing elective diagnostic trans-femoral cerebral angiography; 2.The patient or their representative must sign the informed consent form;
Exclusion criteria
Exclusion criteria: 1.Allergy to heparin or iodinated contrast media, or contraindications; 2.Platelet count < 100 × 10^9/L; or a history of heparin-induced thrombocytopenia; 3.Severe hypertension with poor blood pressure control; 4.High risk of thrombosis (malignant tumours, pregnant or breastfeeding women); 5.Patients in whom preoperative ultrasound has confirmed deep vein thrombosis in the lower limbs; 6.Patients with femoral arteriovenous fistula as indicated by femoral angiography; 7.Patients with a clear bleeding tendency (those with coagulation disorders, severe hepatic or renal impairment, or severe acute infectious diseases); 8.Patients undergoing interventional treatment concurrently with cerebral angiography; 9.Patients deemed by the investigators to be unsuitable for participation in this trial;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Puncture-site complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Non-access site bleeding;Cerebral ischemic event;Venous thromboembolic event (VTE);Postprocedural immobilization time;Postoperative low back pain score;Proportion of postoperative catheterization;Coagulation function and hemoglobin change value; | — |
Countries
China
Contacts
Public ContactLi Kaifeng
Shenzhen Hospital of Southern Medical Unversity
Outcome results
None listed