Chronic exfoliative cheilitis
Conditions
Interventions
Experimental Group A:Photodynamic Therapy
Control group B:Triamcinolone acetonide
Sponsors
West China Hospital of Stomatology, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >=18 years, regardless of gender; 2. The lips are mainly characterized by exfoliation, which can be accompanied by local dry swelling, itching, tingling or burning pain. The condition is repeated and can last for months or even years. 3. Can clearly express their own symptoms and feelings; 4. Participants voluntarily participated in this study and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Those with other types of cheilitis such as actinic cheilitis or glandular cheilitis or contact cheilitis, and those with malignant tumors in the mouth or lips ; 2. Pregnancy or lactation; 3. In the past month, patients received systemic or local treatment for chronic desquamation cheilitis, including the use of glucocorticoids, calcineurin inhibitors, anti-infective drugs, etc. 4. Triamcinolone acetonide or laser, or photodynamic therapy history of allergy; 5. Participants with immune system dysfunction ( such as rheumatoid arthritis, systemic lupus erythematosus, HIV infection, etc. ) or who are using immunosuppressive agents ( such as cyclosporine, methotrexate, etc. ). 6. Participants who could not complete the follow-up of the study ( such as hospitalization, mental disorders, non-cooperation ) and other conditions that the researchers did not consider suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Healing Rate of Scale;Overall Response Rate, ORR; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recurrence Rate;Adverse reaction incidence rate;quality of life; | — |
Countries
China
Contacts
Public ContactZhou Hongmei
West China Hospital of Stomatology, Sichuan University
Outcome results
None listed