Thyroid eye disease upper eyelid retraction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Diagnosis of TED according to the Bartley criteria. 2. Aged >= 18 years and = 1 mm between the affected and contralateral eyes.
Exclusion criteria
Exclusion criteria: 1. Concurrent dry eye due to other causes, such as Sjögren's syndrome; 2. Use of medications affecting tear film or meibomian gland function within the past 3 months; 3. Systemic or topical use of glucocorticoids, immunosuppressants, or biologics within the past 3 months; 4. Contact lens wear; 5. Local injection of botulinum toxin into the eyelids within the past 6 months; 6. Poor quality of meibomian gland images, ocular surface images, or CT images that precludes analysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Parameters of the upper eyelid meibomian glands measured by AI (such as contrast value, density); | — |
Secondary
| Measure | Time frame |
|---|---|
| Tear River Height (TMH);Non-Invasive Tear Break-Up Time, NBUT; | — |
Countries
China
Contacts
Eye Hospital, Wenzhou Medical University