Laparoscopic abdominal surgery
Conditions
Interventions
Ciprofol group:Anesthesia induction: 0.5mg/kg intravenous injection, with an additional dose of 0.2mg/kg.
Anesthesia maintenance: Intravenous infusion at a rate of 0.4~2.4 mg/kg/h until the end of sur
Propofol group:Anesthesia induction: 2.5mg/kg intravenous injection, with an additional dose of 1mg/kg.
Anesthesia maintenance: Intravenous infusion at a rate of 4~12 mg/kg/h until the end of surgery.
Sponsors
The Second Affiliated Hospital of Zunyi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Aged 18-65 2) ASA classification of I-II 3) Patients who are scheduled to undergo laparoscopic abdominal surgery under general anesthesia
Exclusion criteria
Exclusion criteria: 1) Those who have a known history of allergy to the relevant drugs in this scheme; 2) Individuals with severe neurological diseases (such as epilepsy, Parkinson's disease) or those who have experienced a stroke or undergone intracranial surgery within the past 6 months; 3) Individuals with alcohol or drug addiction (physically and psychologically dependent on alcohol or drugs); 4)Hb50mmHg), unstable angina pectoris, or cardiac function NYHA classification of III or above; 11) Patients with liver dysfunction (Child-Pugh Class B and C); 12) Hypothyroidism/Subclinical hypothyroidism; 13)Myasthenia gravis ; 14) Adrenal insufficiency;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of Recovery Score;Consciousness recovery time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean arterial pressure;Heart rate;Tracheal tube removal time;Post-Anesthesia Care Unit dwell time;Patients with Postoperative NRS Score > 3 at 24 Hours;PONV at 24 Hours;vasoactive drugs;Injection pain; | — |
Countries
China
Contacts
Public ContactWang Zhao
The Second Affiliated Hospital of Zunyi Medical University
Outcome results
None listed