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A study on predicting extubation success in mechanically ventilated patients by evaluating diaphragm function with different imaging methods

Predictive Value of Diaphragm Function Indicators Based on CT, Ultrasound and EIT for Extubation Success Rate in Mechanically Ventilated Patients: A Prospective Observational Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600123236
Enrollment
Unknown
Registered
2026-04-23
Start date
2026-05-01
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory failure requiring mechanical ventilation

Interventions

Mechanically ventilated patients cohort:None

Sponsors

The FIrst Affiliated Hospital, College of Medicine, Zhejiang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1.Aged = 18 years and = 85 years; 2.Duration of mechanical ventilation = 48 hours; 3.Signed informed consent;

Exclusion criteria

Exclusion criteria: 1.Pregnant patients; 2.Patients with severe neuromuscular diseases leading to severely impaired diaphragmatic function; 3.Patients with expected survival time < 48 hours; 4.Patients unable to cooperate with diaphragmatic ultrasound or EIT examinations;

Design outcomes

Primary

MeasureTime frame
Electrical Impedance Tomography (EIT) derived metrics;Extubation success outcome within 48 hours;Diaphragmatic cross-sectional area and movement velocity;Diaphragmatic Thickening Fraction (DTF);—

Secondary

MeasureTime frame
Clinical baseline characteristics;—

Countries

China

Contacts

Public ContactXia Zheng

The FIrst Affiliated Hospital, College of Medicine, Zhejiang University

zxicu@zju.edu.cn+86 571 8723 6666

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 1, 2026