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The Application of Serum LDH, CK-MB, and NSE in Predicting the Prognosis of Febrile Seizures in Children

The Application of Serum LDH, CK-MB, and NSE in Predicting the Prognosis of Febrile Seizures in Children

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600123235
Enrollment
Unknown
Registered
2026-04-23
Start date
2026-04-25
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Simple febrile seizures (FS)

Interventions

Control group (Experiencing fever without convulsive seizures):Non
Complex febrile seizures group:None
Simple febrile seizures group:None

Sponsors

Yuebei People’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 6 Years

Inclusion criteria

Inclusion criteria: Observation group: 1. Patients who meet the diagnostic criteria for FC, including a clear history of fever, clinical manifestations of convulsive seizures, and exclusion of other diseases that may cause convulsive seizures; 2. Aged 6 years or younger; 3. Experiencing their first episode; 4. With complete clinical data, including detailed medical history, physical examination results, laboratory test results, and imaging findings; 5. With guardians who are aware of the study content and have voluntarily signed the informed consent form. Control group: 1. Aged 6 years and below; 2. Experiencing fever without convulsive seizures; 3. With guardians who are aware of the study content and have voluntarily signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Previous history of growth retardation; 2. Presence of genetic and metabolic diseases; 3. Previous history of epilepsy; 4. Presence of convulsions caused by intracranial infection, electrolyte imbalance, vitamin D deficiency, and other diseases; 5. Poor compliance, unable to cooperate with the study.

Design outcomes

Primary

MeasureTime frame
Neuron-Specific Enolase, NSE;

Secondary

MeasureTime frame
Lactate Dehydrogenase, LDH;Creatine Kinase (CK) Isoenzyme MB, CK-MB;

Countries

China

Contacts

Public ContactShi Yile

Yuebei People’s Hospital

244638548@qq.com+86 751 6913569

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 1, 2026