Breast cancer surgery
Conditions
Interventions
Group N:Anesthesia induction was performed sequentially via intravenous injection of sufentanil 0.4 µg/kg, propofol 2 mg/kg, and cisatracurium besylate 0.2 mg/kg. After adequate oxygen administration
Group ES:On the basis of Group N , 0.3mg / kg of eszopiclone was given during the induction of anesthesia
Group SG:On the basis of Group ES , 5mL of 0.25% ropivacaine was injected into the right SGB under ultrasound guidance 10min before anesthesia induction
Sponsors
Hainan General Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18-70 years, with a body mass index (BMI) of 18-30 kg/m^2; 2.ASA classification I-II; 3.scheduled for elective unilateral radical or modified radical mastectomy with the ability to complete a two-day 3.postoperative follow-up; 4.capable of fully understanding and accurately assessing the numerical pain scale; 5.conscious, voluntarily signing an informed consent form, and cooperating with experimental testing.
Exclusion criteria
Exclusion criteria: 1.History of bilateral mastectomy or breast tumor resection; 2.poorly controlled hypertension, coronary heart disease, heart disease, increased intracranial pressure, etc.; 3.severe respiratory diseases such as chronic obstructive pulmonary disease or asthma; 4.contraindications for nerve block such as puncture site or systemic infection, coagulation disorders, peripheral neuropathy; 5.hyperthyroidism, goiter, history of thyroid surgery, or frequent coughing; 6.chronic pain, abuse or long-term use of anesthetics, sedatives, or analgesics; 7.allergy to local anesthetics or general anesthetics used during surgery; 8.severe hepatic or renal insufficiency, or neurological, psychiatric, or neuromuscular disorders; 9.women during menstruation, lactation, or pregnancy; 10.other conditions that may affect the study results.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sufentanil dosage;Numerical Rating Scale score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Anxiety and depressive state;Sleep quality ;TNF-a;IL-6; | — |
Countries
China
Contacts
Public ContactLiumei Cai;Duozhi Wu
Hainan General Hospital
Outcome results
None listed